Drug Reactions

Aside from the desired therapeutic effects, a person may also elicit other undesired reactions from the drug he/she is taking. Some may still be tolerated; however, more severe adverse reactions may justify discontinuation of the medicine.

Drug Allergies

A drug allergy is an immunologic response to a drug. Each individual has his own level of sensitivity. In cases of hypersensitivity or hyper responsiveness, the body mistakes the drug as a harmful substance. When a person is exposed to a foreign substance called an antigen, the immune system responds by producing antibodies in a process called sensitization. On succeeding exposures, these antibodies will target the specific drug containing that antigen and develop symptoms of an allergic reaction.

Allergic reactions can be mild or severe. Manifestations range from a mild rash to anaphylactic shock, depending on the dose, the allergen, and the sensitivity of the individual. An allergic reaction can occur anytime from a few minutes to 2 weeks following administration of the medicine. But a severe reaction usually occurs immediately after administration and can be fatal if not treated promptly.

What you Doctor can do for you

Most of the time, allergic reactions to drugs are diagnosed by doing skin tests. The skin may be pricked, scratched, or injected with a small amount of medicine. A positive result is obtained if a large rash occurs on the tested site half an hour after administration. The results must be interpreted by a trained professional or by your allergist.

Some drug allergies are diagnosed by other laboratory exams like blood testing. Thorough physical assessment is very necessary as this will help indicate the severity of the allergic reaction.
As soon as drug allergy is suspected, the medicine is discontinued. Mild allergies can be treated with antihistamines and corticosteroids. If the reaction is severe, epinephrine will be necessary to relieve bronchoconstriction (narrowing of the airways). Other supportive procedures will be ordered by the physician as needed.

What you can do

There is other no valuable treatment for drug allergies than to avoid the drug that causes the allergies. You should know what you are allergic to. If you are a highly sensitive person, have yourself checked properly by an allergist. Always bring your emergency kit with you and do not hesitate to ask for medical help or call 911 as soon as possible once you are starting to experience the symptoms.